Pokeberry

Scientific Name: Phytolacca Americana

Common Name: Pokeweed, Pokeberry, Poke, Inkberry, Pigeonberry

Botanical Description: A large, smooth, branching herb from a large, perennial rootstock, and with green, red, or purple stems; leaves alternate and simple; flowers white, on a long stem, more or less erect; fruit a dark purple berry composed of 5-12 segments fused in a ring, the stem drooping. P. rigida differs by having shorter, erect fruiting stems
The berries are believed to be toxic to humans, but are eaten by birds. It is a native of northeastern North America where it is a common weed of disturbed, usually fertile, soils. The closely related Indian pokeberry, P. acinosa, is quite similar in appearance.

Range: Forest or natural areas, weedy in disturbed areas, in fields, fence rows, low grounds, clearings, waste places, roadsides.

Cultural Uses: The fresh and very young spring-time greens of the pokeberry were boiled, drained, and boiled again to make "poke salad" the traditional rural dish in the southern U.S. immortalized in the 1960's hit song "Poke Salad Annie". The plant is generally poisonous so this, and all other uses of this plant are not recommended without the guidance of a seasoned expert. This plant contains chemicals called the "pokeweed mitogens" that are being studied for use in treatments of autoimmune diseases including AIDS and rheumatoid arthritis. Mitogens are substances that promote cell division and may activate mitosis in animal cells that normally would not divide. Some lectins, e.g. those in pokeweed mitogens, can activate mitosis in white blood cells; it is this property that is of interest to AIDS researchers. Pokeweed is also being studied as an agent to combat fungal infections. The berries of the Indian pokeberry have been used for dye production.

Edible Parts: Young tender leaves eaten only as thoroughly cooked greens (in two waters). Cooked berries are safe for making pies. CAUTION: Berries, roots and mature plants are poisonous, therefore, only use as new, young growth. Also any red-tinged plant material should be discarded. To avoid possibly collecting part of the toxic root, do not cut below ground level.

Harvest: Only collect young shoots from areas you know have NOT been treated with pesticides. Collect in early spring. SAFE HANDLING PROCEDURES: Wash young shoots thoroughly with warm water. Do not use dish detergent or any type of sanitizer. These products can leave a residue. Peel and parboil tender young shoots (less than eight inches) in two changes of water several minutes each. Boil in a third water until tender and serve like asparagus. Young stalks less than one foot tall, with leaves removed, and before red tinged, can be cut and rolled in corn meal and fried like okra. They can also be pickled. Young leaves taken from stalks less than one foot tall can be parboiled in two changes of water for several minutes each and
boiled in a third water until tender. To freeze, parboil leaves twice, cook, pat dry and place them in plastic bags. (SOURCE: Larson, Ken. 1995. God's Free Harvest, Rhema Publishing, Inc., Suwanee, GA. 231 pp.)

Active Compounds: Toxic principle: Phytolaccatoxin and related triterpene saponins, an alkaloid (phytolaccin), and histamines.

Toxicity Rating: Low.

Animals Affected: All animals may potentially be affected.

Dangerous Parts of Plant: All parts, especially roots and seeds.

Class of Signs: Gastrointestinal irritation (colic, diarrhea which may be bloody). Rarely: anemia, possibly death. Birth defects and tumors may also be possible.

Animals do not voluntarily eat this plant unless there is no other forage available. If the animals are forced to eat pokeweed (especially if it has been incorporated into processed feeds), the primary signs relate to the irritant effects of the saponin toxins, in particular phytolaccigenin. Salivation, abdominal pain, diarrhea (which may become bloody) can be noted. Horses and ruminants do not exhibit vomiting, which is seen in humans, dogs, cats, and pigs. Signs usually resolve within a day or two. Only if large doses are consumed will the animal display more serious signs: anemia, alterations in the heart rate and in respiration, and in very rare cases, death.

Noted in the human literature but not well published in the veterinary literature is the mutagenic and teratogenic properties of pokeweed, that is the ability to induce mutations (and possibly cancer) and birth defects. For humans, even handling the plant is considered dangerous, so it would seem wise to not only prevent human contact with the plant, but animal contact as well. Despite this, the plant is eaten as a spring vegetable in the southern U.S. after cooking it first in several changes of water. Consumption of the plant is not advised.

First Aid: For gastrointestinal irritation, provide better feed and symptomatic care, and signs should abate in about 24 hours. Discard all feeds containing pokeweed, since the plant is never safe for consumption. For severely affected animals, or if it is known that a large amount was consumed, consult a veterinarian promptly for emergency care

Prevention: Pokeweed should be removed from pastures and barnyards. Exercise caution when doing so, since the plant is toxic to humans as well. Good pasture management, with mowing and weed removal, will suffice in keeping pokeweed under control.

Research: Used by Harry Hoxsey in a controversial cure for Cancer (in conjunction with other herbs). The formula is under long term study at the University of Texas School of Public Health. Early results are encouraging.

Silver Lupine

COMMON NAMES:Lupine, Bluebonnet, Quaker-Bonnets

LATIN NAME:Lupinus perennis (wild)
Lupinus polyphyllus (cultivated)
(pea family)

TOXICITY RATING: Low to moderate in Indiana. In the western rangelands, where lupine grows plentifully, the risk of toxicosis would be high. Different species of lupine have different toxicities. According to reports, L. leucophyllus (velvet or wooly-leafed lupine) is the most toxic and should never be grazed since all stages of plant growth are toxic.

ANIMALS AFFECTED: Sheep are primarily affected, but all animals are susceptible.

DANGEROUS PARTS OF PLANT: All parts, especially pods with seeds.

CLASS OF SIGNS: Breathing problems, behavioral changes, trembling, birth defects, coma, death.

PLANT DESCRIPTION: Lupines (fig. 6) are herbaceous perennials grown in gardens or found wild along roadsides, in fields, and in open woods. Wild lupines are common only in the prairie and lake counties of Indiana. In the rangelands of the West, they are a leading cause of livestock poisoning. Several stems often grow from one creeping root and reach 12 to 30 inches in height. The leaves are alternate and pal-
mately compound with 7 to 11 spear-tip-shaped, softly hairy segments. Elongate spikes of blue, purple, white, magenta, or bicolored pea-like flowers in early summer are followed by 1- to 2-inch, fuzzy, pea-like pods.

SIGNS: Toxicity in lupine is believed to result primarily from the alkaloid D-lupanine. The signs of lupine poisoning can develop within an hour or may take as long as a day. The signs are related to the nervous system and resemble the signs seen with excessive consumption of nicotine (tobacco): twitching, nervousness, depression, difficulty in moving and breathing, and loss of muscular control. If large quantities were consumed, convulsions, coma, and death by respiratory paralysis may occur. In cows that graze lupine, skeletal birth defects in calves can occur, and the syndrome is called "crooked calf".

FIRST AID: There is no antidote. Allow affected livestock to rest quietly, especially if they are unfamiliar with human contact. Handling, trailering, or other stress on the animals after they have been grazing lupine will make the signs worse and can increase losses.

SAFETY IN PREPARED FEEDS: The alkaloids in lupine remain after the plants have dried, so prepared feeds are unsafe for consumption, especially if the feeds contain lupine seed pods.

PREVENTION: Do not allow hungry animals access to lupine, particularly when in the seed stage, if other forage is not available. If lupines are prevalent in the pasture, become familiar with the particular species, since toxicities vary. Do not handle, process, or ship animals that are heavily grazing lupine since this type of stress will increase the number of animals that will become sick and/or die. Livestock can graze lupine without incident as long as excessive ingestion is avoided and animals are not handled or trailered while on lupine pastures (and if the animals are not pregnant). In cattle, to avoid birth defects, do not allow grazing between days 40 and 70 of gestation.